Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
Diagnostics
Establishing
the diagnosis of autoimmune disease, SLE, is a multistep process. Diagnosticum
Zrt. is developing multiplex serological protein microarrays based on AbC-array technology
/PCT/HU2007/000064/. These chips are for the simultaneous assessment of
autoantibody levels and complement fixing properties, in a multiplex format. The
prototype lupus diagnostic chip measures 8 autoantibodies (C1q, histone,
chromatin, dsDNA, ssDNA, SSA, Sm, RibP) and their complement fixation for an
increased diagnostic efficiency and simplified laboratory testing scheme.
Project is
supported by the grant KMOP-1.1.1-08/1-2008-0028 from the National Development
Agency and European Union Regional Development Found