Systemic Lupus Erythematosus (SLE) Diagnostics
Establishing the diagnosis of autoimmune disease, SLE, is a multistep process.
Diagnosticum Zrt. is developing multiplex serological protein microarrays based on AbC-array technology /PCT/HU2007/000064/. These chips are for the simultaneous assessment of autoantibody levels and complement fixing properties, in a multiplex format. The prototype lupus diagnostic chip measures 8 autoantibodies (C1q, histone, chromatin, dsDNA, ssDNA, SSA, Sm, RibP) and their complement fixation for an increased diagnostic efficiency and simplified laboratory testing scheme.
(Product under development)

Diabetes Diagnostics
Type 2 diabetes mellitus is accompanied by changes not only in metabolic functions, but it also has immunological aspects, such as inflammatory reactions in the adipose tissue. Diagnosticum Zrt. is developing Immunological assays on protein microarrays that can track these alterations in various pre-diabetic conditions. Serological testing of metabolites characterizing the pre-diabetic state could reveal novel aspects of the disease pathogenesis.
(Product under development) 

HbA1c Diagnostics
For the quantitative determination of Hemoglobin A1c (HbA1c) in human blood.  The determination of HbA1c is most commonly performed for the evaluation of glycemic control in diabetes mellitus. HbA1c values provide an indication of glucose levels over the preceding 4-8 weeks. A higher HbA1c value indicates poorer glycemic control.
This method utilizes the interaction of antigen and antibody to directly determine the HbA1c in whole blood. Total hemoglobin and HbA1c have the same unspecific absorption rate to latex particles. When mouse antihuman HbA1c monoclonal antibody is added (R2), latex-HbA1c-mouse anti human HbA1c antibody complex is formed. Agglutination is formed when goat anti-mouse IgG polyclonal antibody interacts with the monoclonal antibody. The amount of agglutination is proportional to the amount of HbA1c absorbed on to the surface of latex particles. The amount of agglutination is measured as absorbance. The HbA1c value is obtained from a calibration curve.